Back to Search
Start Over
Does gastric bypass alter alcohol metabolism?
- Source :
- Surgery for Obesity & Related Diseases; Sep2007, Vol. 3 Issue 5, p543-548, 6p
- Publication Year :
- 2007
-
Abstract
- Abstract: Background: Morbid obesity is the leading public health crisis in the United States, with bariatric surgery as the only effective and enduring treatment for this disease. a concern has been raised, that, postoperatively, alcohol metabolism might be altered in gastric bypass patients. We hypothesized that alcohol metabolism in the postoperative gastric bypass patient would be altered. Methods: Of 36 subjects, 17 control and 19 postgastric bypass subjects each consumed 5 oz of red wine. They underwent an alcohol breath analysis every 5 minutes. The outcomes recorded included symptoms, initial peak alcohol breath level, and the time for alcohol breath levels to normalize. Results: The gastric bypass group was on average 10 years older and had a greater weight and body mass index than the control group. The average time after gastric bypass was 2 years, with an average body mass index loss of 18 kg/m<superscript>2</superscript> (51 kg/m<superscript>2</superscript> before versus 33 kg/m<superscript>2</superscript> after). The gastric bypass patients had a peak alcohol breath level of 0.08% and the controls had a level of 0.05%. The gastric bypass group needed, on average, 108 minutes to reach an alcohol breath level of 0; the control group reached this level after an average of 72 minutes. Both groups showed a similar postingestion symptom profile. Conclusion: In this study, alcohol metabolism was significantly different between the postgastric bypass and control subjects. Although the gastric bypass patients’ had a greater peak alcohol level and a longer time for the alcohol level to reach 0 than the controls, the gastric bypass group did not experience more symptoms than the control group. These findings provide caution regarding alcohol use by gastric bypass patients. [Copyright &y& Elsevier]
- Subjects :
- GASTRIC bypass
BODY weight
METABOLISM
BARIATRIC surgery
Subjects
Details
- Language :
- English
- ISSN :
- 15507289
- Volume :
- 3
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Surgery for Obesity & Related Diseases
- Publication Type :
- Academic Journal
- Accession number :
- 26844847
- Full Text :
- https://doi.org/10.1016/j.soard.2007.07.003