Multiple aneurysms of the facial artery in hereditary hemorrhagic teleangiectasia—Case report and review of the literature.

Abstract: This report describes the infrequent case of the occurrence of eight aneurysms of the facial artery in association with hereditary hemorrhagic teleangiectasia (HHT, Rendu–Osler–Weber disease, ROW). The aneurysms and the teleangiectatic nodules of the tongue were successfully treated by endovascular embolization in a combined technique using particles (polyvinyl alcohol, PVA) and fibred platinum coils. Endothelial cell degeneration, fragmentation of the elastic lamina and loss of muscularis in the vessel wall may be causal and give rise to multiple aneurysms of the intracranial and extracranial circulation in hereditary hemorrhagic teleangiectasias. This case and a review of the literature are presented because in the literature neither combined occurrence of ROW with a single aneurysm nor with multiple aneurysms of extracranial vessels are described. [Copyright &y& Elsevier]