Indirect Enantioseparation by HPLC Using Chiral Benzofurazan-Bearing Reagents.

The chiral resolutions by high-performance liquid chromatography (HPLC) are divided into the following three: one is direct resolution using a chiral stationary phase (CSP); another relies on diastereomer formation with a suitable chiral derivatization reagent; a third technique is a minor method utilizing chiral mobile phase additives. [ABSTRACT FROM AUTHOR]