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Promoter Hypermethylation of the p16 Gene Is Associated with Poor Prognosis in Recurrent Early-Stage Hepatocellular Carcinoma.
- Source :
- Cancer Epidemiology, Biomarkers & Prevention; Sep2008, Vol. 17 Issue 9, p2260-2267, 8p, 3 Charts, 4 Graphs
- Publication Year :
- 2008
-
Abstract
- The article discusses the result of a study concerning the association of promoter hypermethylation of the p16 gene with poor prognosis in recurrent early-stage hepatocellular carcinoma. It was found that negative expression of p16 at a protein level is associated with poor survival in recurrent stage I to II hepatocellular cancer.
Details
- Language :
- English
- ISSN :
- 10559965
- Volume :
- 17
- Issue :
- 9
- Database :
- Supplemental Index
- Journal :
- Cancer Epidemiology, Biomarkers & Prevention
- Publication Type :
- Academic Journal
- Accession number :
- 34263262
- Full Text :
- https://doi.org/10.1158/1055-9965.EPL-O8-0236