Supplementation with a whey protein hydrolysate enhances recovery of muscle force-generating capacity following eccentric exercise.

Abstract: There is evidence that protein hydrolysates can speed tissue repair following damage and may therefore be useful for accelerating recovery from exercise induced muscle damage. The potential for a hydrolysate (WPI_HD) of whey protein isolate (WPI) to speed recovery following eccentric exercise was evaluated by assessing effects on recovery of peak isometric torque (PIT). In a double-blind randomised parallel trial, 28 sedentary males had muscle soreness (MS), serum creatine kinase (CK) activity, plasma TNFα, and PIT assessed at baseline and after 100 maximal eccentric contractions (ECC) of their knee extensors. Participants then consumed 250ml of flavoured water (FW; n =11), or FW containing 25g WPI (n =11) or 25g WPI_HD (n =6) and the assessments were repeated 1, 2, 6 and 24h later. PIT decreased ∼23% following ECC, remained suppressed in FW and WPI, but recovered fully in WPI_HD by 6h (P =0.006, treatment×time interaction). MS increased following ECC (P <0.001 for time), and remained elevated with no difference between groups (P =0.61). TNFα and CK did not change (P >0.45). WPI_HD may be a useful supplement for assisting athletes to recover from fatiguing eccentric exercise. [Copyright &y& Elsevier]