Serum neutralization with different types and subtypes of bovine herpesvirus 1 and 5.

The article discusses research on the sensitivity of serum neutralization (SN) tests with various types and subtypes of bovine herpesvirus 1 and 5 as challenge viruses. The SN test is recognized as a gold standard method that may be used for the measurement of neutralizing antibodies to bovine herpesviruses. The study procedure included the incubation of serum-virus mixtures at 37-degree Celsius. Results revealed differences in the sensitivity of SN which depended on the challenge virus applied in the test.