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Effects of Daintain/AIF-1 on βCell Dysfunction in INS-i Cells.
- Source :
- Bioscience, Biotechnology & Biochemistry; Sep2011, Vol. 75 Issue 9, p1842-1844, 3p
- Publication Year :
- 2011
-
Abstract
- The article focuses on the effects of daintain/allograft inflammatory factor-1 (AIF-1) on INS-1β cells. It states that decreased cell viability and glucose-stimulated insulin secretion and upregulated apoptosis were revealed after cells were incubated with daintain/AIF-1. Moreover, it mentions that daintain/AIF-1 plays a vital role in the dysfunction of pancreatic β cells in type-1 (insulin-dependent) diabetes (TID).
- Subjects :
- PANCREATIC beta cells
INSULIN
APOPTOSIS
TYPE 1 diabetes
CYTOLOGICAL research
Subjects
Details
- Language :
- English
- ISSN :
- 09168451
- Volume :
- 75
- Issue :
- 9
- Database :
- Supplemental Index
- Journal :
- Bioscience, Biotechnology & Biochemistry
- Publication Type :
- Academic Journal
- Accession number :
- 67653735
- Full Text :
- https://doi.org/10.1271/bbb.110317