Correlation of Amyloid PET Ligand Florbetapir F 18 Binding With Aβ Aggregation and Neuritic Plaque Deposition in Postmortem Brain Tissue.

The article presents a study that investigates the quantitative correlations between florbetapir F 18 tissue binding with Aβ aggregation. It states that the study used human autopsy brain tissue to evaluate the correlation between florbetapir F 18 binding and Aβ density measured using neuropathologic method. It notes that the result supported the use of florbetapir F 18 as an amyloid positron emission tomography (PET) ligand to identify the presence of Alzheimer disease pathology.