Fatal Canid herpesvirus 1 infection in an adult dog.

The article presents a study which examines the case of fatal Canid herpesvirus 1 (CaHV-1) infection in a 9-year-old spayed female Bichon Frise dog. It observes the intranuclear inclusion bodies in the adrenal gland of the CaHV-1-infected puppies. It confirms the CaHV-1 infection by doing immunohistochemistry, in situ hybridization, and polymerase chain reaction to the liver samples. Results have showed that CaHV-1 should be included in the diagnosis of hepatic necrosis in adult dogs.