Genetic variation analysis of ORF5 gene of Liaoning LN/0901 strain PRRSV and prediction of its antigenic sites.

The article offers information on a study on open reading frame five (ORF5) gene of porcine reproductive and respiratory syndrome virus's (PRRSV's) Liaoning LN/0901 strain and its genetic variation analysis. It informs that Reverse transcriptase polymerase chain reaction (RT-PCR) and amino acid hydrophobicity were performed on ORF5 gene fragments and their antigenic sites were predicted. The study concluded that PRRS genetically engineered vaccine having Liaoning region can be developed.