Randomized Controlled Trial of Interventions for Young People at Ultra-High Risk of Psychosis: Twelve-Month Outcome.

The article presents a randomized controlled trial of interventions for young people at ultra-high risk of psychosis over a 12-month period. The aim of the study is to determine which intervention is most effective at preventing transition to psychosis-cognitive therapy plus low-dose risperidone, cognitive therapy plus placebo or supportive therapy plus placebo. It concluded that all three failed to provide support for antipsychotic drugs but supportive therapy is likely to be effective.