Synthesis of 4, 10-Dinitro-2, 6, 8, 12-Tetraoxa-4, 10-Diazatetracyclo-[5. 5. 0. 05, 903, 11]-Dodecane.

This paper studies two-step synthetic process of TEX (4,10-dinitro-2,6, 8,12-tetraoxa-4, 10-diazatetracyclo-[5. 5. 0. 0^5,9 0^3,11]-dodecane) and the effects of key factors on the yield of DFTHP (intermediate) and TEX. The results show that the yield of DFTHP could reach to 68. 3% when the adjusted pH value of reaction solution reaches to 9 by saturated NaOH solution. When the volume ratio of fuming HNO3 to concentrated H2SO4 is 3 : 2, and the ratio of nitrating agent (mL) to DFTHP(g) is 3 : 1, the yield of TEX raises to 59. 7% . The optimized overall yield of TEX obtained from two-step synthetic process could be 40. 8%. [ABSTRACT FROM AUTHOR]