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Perinatal multiple exposure to neurotoxic (lead, methylmercury, ethylmercury, and aluminum) substances and neurodevelopment at six and 24 months of age.
- Source :
- Environmental Pollution; Apr2014, Vol. 187, p130-135, 6p
- Publication Year :
- 2014
-
Abstract
- We studied neurodevelopment in infants from two communities. Children living in the vicinity of tin-ore kilns and smelters – TOKS; n = 51) were compared to children from a fishing village (Itapuã; n = 45). Mean hair-Hg (HHg) concentrations were significantly higher in Itapuã children which received significantly (p = 0.0000001) less mean ethylmercury (88.6 μg) from Thimerosal-containing vaccines (TCV) than the TOKS children (120 μg). Breast-milk Pb concentrations were significantly higher in the TOKS mothers (p = 0.000017; 10.04 vs. 3.9 μg L<superscript>−1</superscript>). Bayley mental development index (MDI) and psychomotor development index (PDI) were statistically significant (respectively p < 0.0000001, p = 0.000007) lower for the TOKS children only at 24 months of age. Multivariate regression analysis showed that MDI was negatively affected by breast-milk Pb and by HHg. PDI was positively affected by breastfeeding and negatively affected by ethylmercury. Milestone achievements were negatively affected by breast-milk Pb (age of walking) and by HHg (age of talking). [Copyright &y& Elsevier]
Details
- Language :
- English
- ISSN :
- 02697491
- Volume :
- 187
- Database :
- Supplemental Index
- Journal :
- Environmental Pollution
- Publication Type :
- Academic Journal
- Accession number :
- 94578312
- Full Text :
- https://doi.org/10.1016/j.envpol.2014.01.004