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Synthesis of a C-linked Antifreeze Glycoprotein (AFGP) Mimic:  Probes for Investigating the Mechanism of Action

Authors :
Ben, R. N.
Eniade, A. A.
Hauer, L.
Source :
Organic Letters; December 1999, Vol. 1 Issue: 11 p1759-1762, 4p
Publication Year :
1999

Abstract

<UFIGR ID="ol9910251n00002">A general convergent synthesis has been developed to afford a low molecular weight C-linked antifreeze glycoprotein (AFGP) mimic (<BO>9</BO>). Structural mimics of AFGPs have tremendous potential as probes to better understand how native AFGPs inhibit ice crystal growth in organisms that inhabit subzero environments.

Details

Language :
English
ISSN :
15237060 and 15237052
Volume :
1
Issue :
11
Database :
Supplemental Index
Journal :
Organic Letters
Publication Type :
Periodical
Accession number :
ejs1159645