Quantitative Doppler blood flow measurement method and in vivo calibration

Femoral blood flow (FBF) was measured in seven dogs, simultaneously with both an electromagnetic perivascular probe and a transcutaneous range gated Doppler velocimeter. Measurements were made in basal conditions and during intraarterial infusions of noradrenaline (10 to 400 ng·kg–1min–1) and isoprenaline (10 to 400 ng·kg–1·min–1) thus allowing comparisons of ultrasonic (DBF) and electromagnetic (EMBF) blood flow at 91 different blood flow rates ranging from 5 to 300 cm3·min–1. The linear regression line through the data of ultrasonic and electromagnetic simultaneous measurements was:<$O_FD> <IMG BORDER=0 WIDTH=112 HEIGHT=6 SRC="<$FIGDIR>/medium/19-11-700-si1.gif" ALT="Formula "<$INLINEFIG_ALIGN>><$C_FD>with a highly significant correlation (r = 0.96, p>0.001) but there was a wide scattering about the mean. Errors in DBF were mainly due to positioning of the probe and determination of arterial diameter.