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Treatment of cerebrospinal fluid shunt infections with teicoplanin
- Source :
- European Journal of Clinical Microbiology & Infectious Diseases; December 1994, Vol. 13 Issue: 12 p1056-1058, 3p
- Publication Year :
- 1994
-
Abstract
- Intraventricular teicoplanin 10–15 mg was administered daily to three patients with cerebrospinal fluid (CSF) shunt infections due toStaphylococcus epidermidis andEnterococcus faecalis. Teicoplanin concentrations in CSF 24 h after intrathecal injection of the drug exceeded four- to eight-fold the MICs for the infecting microorganisms. CSF cultures rapidly became negative and shunt devices were withdrawn and replaced in the same operative procedure. Intraventricular teicoplanin was well tolerated. No relapses occurred. Teicoplanin may be an alternative to vancomycin for the antimicrobial therapy of CSF shunt infections.
Details
- Language :
- English
- ISSN :
- 09349723 and 14354373
- Volume :
- 13
- Issue :
- 12
- Database :
- Supplemental Index
- Journal :
- European Journal of Clinical Microbiology & Infectious Diseases
- Publication Type :
- Periodical
- Accession number :
- ejs15478736
- Full Text :
- https://doi.org/10.1007/BF02111827