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Itraconazole vs amphotericin B: in vitro comparative evaluation of the minimal inhibitory concentration (MIC) against clinically isolated yeasts

Authors :
Lombardi, G.
Gramegna, G.
Cavanna, C.
Poma, G.
Marangoni, E.
Michelone, G.
Source :
Mycopathologia; April 1989, Vol. 106 Issue: 1 p31-34, 4p
Publication Year :
1989

Abstract

Itraconazole is a triazole compound which, following several clinical trials, has begun to be used for therapy of mycotic infections. This new drug, with a broad-spectrum antifungal activity, can be orally administered. The Authors studied the in vitro susceptibility to amphotericin B and itraconazole of the following clinical isolates of pathogenic yeasts: 100 Candida albicans, 20 C. tropicalis, 20 C. parapsilosis, 8 C. guilliermondii, 6 C. pseudotropicalis, 24 Torulopsis glabrata and 16 Cryptococcus neoformans.

Details

Language :
English
ISSN :
0301486X and 15730832
Volume :
106
Issue :
1
Database :
Supplemental Index
Journal :
Mycopathologia
Publication Type :
Periodical
Accession number :
ejs15619655
Full Text :
https://doi.org/10.1007/BF00436923