Synthesis of macrolide antibiotics Communication 7. New synthesis of C9-C13 fragment of erythronolide A

Conclusions 1.An effective scheme of synthesis of 1,6-anhydro-2-desoxy-2-C-methyl-3-O-benzyl-4-methylene-ß-D-xylohexapyranose, an important intermediate compound in the synthesis of macrolide antibiotics, has been developed.2.A C⁹-C¹³ fragment of erythronolide A was synthesized in 14 stages from levoglucosan to give an overall yield of 7.5%.