Back to Search Start Over

Antibody catalyzed modification of amino acids. Efficient hydrolysis of tyrosine benzoate

Authors :
Benedetti, Fabio
Berti, Federico
Flego, Massimiliano
Peressini, Silvia
Colombatti, Alfonso
Gardossi, Lucia
Linda, Paolo
Source :
Chemical Communications; April 21, 2001, Vol. 2001 Issue: 8 p715-716, 2p
Publication Year :
2001

Abstract

Esterase antibody 522c2, the first example of a catalytic antibody specifically programmed to control the reactivity of functional groups on the side chain of tyrosine, accelerates the hydrolysis of benzoate esters of l-tyrosine and tyrosine-containing dipeptides by a factor of 10<SUP>4</SUP> and is moderately active against other benzoate esters.

Details

Language :
English
ISSN :
13597345 and 1364548X
Volume :
2001
Issue :
8
Database :
Supplemental Index
Journal :
Chemical Communications
Publication Type :
Periodical
Accession number :
ejs1700452