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Identification of solvents of abuse using gas chromatography/Fourier transform infrared spectrometry after headspace sampling
- Source :
- Chromatographia; September 1987, Vol. 23 Issue: 9 p626-630, 5p
- Publication Year :
- 1987
-
Abstract
- Summary: After experimental intoxication of rats, gas chromatography — Fourier transform infrared spectrometry with headspace sampling (HS/GC/FT-IR) was used to identify solvents of abuse in biological material (blood, liver, lungs and brain). Limits of detection were measured for acetone, 2-butanone, ether, toluene and trichlorethylene with standard solutions. All the solvents have been identified in the organs of the intoxicated rats. For blood samples a salting-out effect was obtained with potassium carbonate. HS/GC/FT-IR allowed the identification of metabolites of acetone (isopropanol) and of 2-butanone (2-butanol) in blood and organs.
Details
- Language :
- English
- ISSN :
- 00095893 and 16121112
- Volume :
- 23
- Issue :
- 9
- Database :
- Supplemental Index
- Journal :
- Chromatographia
- Publication Type :
- Periodical
- Accession number :
- ejs17139665
- Full Text :
- https://doi.org/10.1007/BF02311489