Sequential 1,3‐Dipolar Cycloaddition of Nitrones to β‐(2‐Aminophenyl) α,β‐Ynones and Cyclocondensation: A New Entry to the Isoxazolino[4,5‐c]quinoline Ring

The reaction of β‐(2‐aminophenyl) α,β‐ynones with N‐methyl nitrones provides a simple and efficient entry to the isoxazolino[4,5‐c]quinoline ring system through a sequential 1,3‐dipolar cycloaddition/annulation process. (© Wiley‐VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2009)