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Gene by Environment Interaction: The −159C/TPolymorphism in the Promoter Region of the CD14Gene Modifies the Effect of Alcohol Consumption on Serum IgE Levels
- Source :
- Alcoholism: Clinical and Experimental Research; January 2006, Vol. 30 Issue: 1 p7-14, 8p
- Publication Year :
- 2006
-
Abstract
- Background: Serum IgE is increased in heavy drinkers. Endotoxin mediates most of the immunological alterations associated with heavy drinking. The −159C/Tpolymorphism in the promoter region of the gene encoding CD14 (an endotoxin receptor) is associated with serum IgE levels in different populations.
Details
- Language :
- English
- ISSN :
- 01456008 and 15300277
- Volume :
- 30
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- Alcoholism: Clinical and Experimental Research
- Publication Type :
- Periodical
- Accession number :
- ejs19435606
- Full Text :
- https://doi.org/10.1111/j.1530-0277.2006.00007.x