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Polymer-Supported O-Methylisourea: A New Reagent for the O-Methylation of Carboxylic Acids
- Source :
- Organic Letters; March 2002, Vol. 4 Issue: 6 p1035-1037, 3p
- Publication Year :
- 2002
-
Abstract
- <UFIGR ID="ol025633sn00001">A solid-supported O-methylisourea reagent has been prepared in one step starting from commercially available solid-supported carbodiimide. The isourea reagent has been successfully used for the preparation of methyl esters from the corresponding carboxylic acids. The crude products obtained after resin filtration and solvent evaporation are generally obtained in >98% purity.
Details
- Language :
- English
- ISSN :
- 15237060 and 15237052
- Volume :
- 4
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Organic Letters
- Publication Type :
- Periodical
- Accession number :
- ejs2072047
- Full Text :
- https://doi.org/10.1021/ol025633s