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Lithiation of Nprotecteddihydro1,4benzoxaziness
- Source :
- Journal of Heterocyclic Chemistry; July 2006, Vol. 43 Issue: 4 p1125-1127, 3p
- Publication Year :
- 2006
-
Abstract
- Lithiation of Nprotected2,3dihydro1,4benzoxazines is described. Lithiation of Ntertbutoxycarbonyl2,3dihydro1,4benzoxazine 1 with BuLiTMEDA occurred in the αposition to nitrogen on the heterocyclic ring, leading to the unexpected ringopened product 3. On the other hand, lithiation of Nmethyl2,3dihydro1,4benzoxazine 4 took place at the oxygenadjacent orthoposition of the aromatic ring.
Details
- Language :
- English
- ISSN :
- 0022152X and 19435193
- Volume :
- 43
- Issue :
- 4
- Database :
- Supplemental Index
- Journal :
- Journal of Heterocyclic Chemistry
- Publication Type :
- Periodical
- Accession number :
- ejs21009689
- Full Text :
- https://doi.org/10.1002/jhet.5570430448