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Albumin-controlled stereoselective reduction of 1,3-diketones to anti-diols

Authors :
Benedetti, Fabio
Berti, Federico
Donati, Ivan
Fregonese, Massimo
Source :
Chemical Communications; April 11, 2002, Vol. 2002 Issue: 8 p828-829, 2p
Publication Year :
2002

Abstract

An unprecedented combination of high chemo- and stereoselectivity in the NaBH<SUB>4</SUB> reduction of 1∶1 complexes between albumin and aromatic 1,3-diketones results in the formation of anti 1,3-diols with de up to 96%.

Details

Language :
English
ISSN :
13597345 and 1364548X
Volume :
2002
Issue :
8
Database :
Supplemental Index
Journal :
Chemical Communications
Publication Type :
Periodical
Accession number :
ejs2129227