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Synthesis and Cholera Toxin Binding Properties of a Lactose-2-aminothiazoline Conjugate
- Source :
- Organic Letters; May 2002, Vol. 4 Issue: 10 p1807-1808, 2p
- Publication Year :
- 2002
-
Abstract
- <UFIGR ID="ol025909wn00001">During the search for improved monovalent ligands for cholera toxin (CT), a new lactose-2-aminothiazoline conjugate was discovered. In a fluorescence binding assay the compound was found to be one of the strongest relatively simple CT ligands to date with a K<INF>d</INF> of 23 μM.
Details
- Language :
- English
- ISSN :
- 15237060 and 15237052
- Volume :
- 4
- Issue :
- 10
- Database :
- Supplemental Index
- Journal :
- Organic Letters
- Publication Type :
- Periodical
- Accession number :
- ejs2180578
- Full Text :
- https://doi.org/10.1021/ol025909w