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Dynamic Kinetic Resolution of β‐Amino Esters by a Heterogeneous System of a Palladium Nanocatalyst and Candida antarcticaLipase A
- Source :
- European Journal of Organic Chemistry; April 2011, Vol. 2011 Issue: 10 p1827-1830, 4p
- Publication Year :
- 2011
-
Abstract
- A dynamic kinetic resolution (DKR) of β‐amino esters have been developed by the use of a heterogeneous racemization catalyst and an immobilized enzyme that accepts aromatic, heteroaromatic and aliphatic substrates. The reaction conditions were optimized to yield an efficient catalytic system without by‐product formation. The products are obtained in 96–99 % eeand high yields.
Details
- Language :
- English
- ISSN :
- 1434193X and 10990690
- Volume :
- 2011
- Issue :
- 10
- Database :
- Supplemental Index
- Journal :
- European Journal of Organic Chemistry
- Publication Type :
- Periodical
- Accession number :
- ejs23442415
- Full Text :
- https://doi.org/10.1002/ejoc.201001714