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Dynamic Kinetic Resolution of β‐Amino Esters by a Heterogeneous System of a Palladium Nanocatalyst and Candida antarcticaLipase A

Authors :
Engström, Karin
Shakeri, Mozaffar
Bäckvall, Jan‐E.
Source :
European Journal of Organic Chemistry; April 2011, Vol. 2011 Issue: 10 p1827-1830, 4p
Publication Year :
2011

Abstract

A dynamic kinetic resolution (DKR) of β‐amino esters have been developed by the use of a heterogeneous racemization catalyst and an immobilized enzyme that accepts aromatic, heteroaromatic and aliphatic substrates. The reaction conditions were optimized to yield an efficient catalytic system without by‐product formation. The products are obtained in 96–99 % eeand high yields.

Details

Language :
English
ISSN :
1434193X and 10990690
Volume :
2011
Issue :
10
Database :
Supplemental Index
Journal :
European Journal of Organic Chemistry
Publication Type :
Periodical
Accession number :
ejs23442415
Full Text :
https://doi.org/10.1002/ejoc.201001714