Underdiagnosis of Vertebral Fractures Is a Worldwide Problem: The IMPACT Study

Accurate radiographic diagnosis of vertebral fractures is important. This multicenter, multinational study assessed radiographic diagnoses of vertebral fracture in 2451 postmenopausal women with osteoporosis. Comparison between local and central readings yielded a false‐negative rate of 34%. Underdiagnosis of vertebral fracture is a worldwide problem.