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The GNAS1T393C Polymorphism Predicts Survival in Patients With Advanced Squamous Cell Carcinoma of the Larynx
- Source :
- The Laryngoscope; December 2008, Vol. 118 Issue: 12 p2172-2176, 5p
- Publication Year :
- 2008
-
Abstract
- Objectives/Hypothesis:In previous studies, we have demonstrated that the T‐allele of a specific single nucleotide polymorphism (SNP) in the Gαs gene (T393C) correlates with increased Gαs expression and hence apoptosis. The T‐allele was associated with a favorable outcome in a variety of human cancers, for example, carcinoma of the urinary bladder, kidney, colorectal, oro‐ and hypopharynx.
Details
- Language :
- English
- ISSN :
- 0023852X and 15314995
- Volume :
- 118
- Issue :
- 12
- Database :
- Supplemental Index
- Journal :
- The Laryngoscope
- Publication Type :
- Periodical
- Accession number :
- ejs24895046
- Full Text :
- https://doi.org/10.1097/MLG.0b013e318185793ds