CLEVELAND DERMATOLOGICAL SOCIETY

Localized Scleroderma. Presented by Dr. W. R. Hubler.A. E., a white woman aged 68, presented from the department of dermatology and syphilology, University Hospitals, has had a small white area with a slight red flare in the umbilicus and another over the right tibia for nine years. For three years numerous pruritic blebs have been appearing on the lesion on the leg, which has slowly increased in size. The patient traumatized this area two months ago, and a small ulcer has developed. Dyspnea and edema of both legs have been present for ten years.There is a large palm-sized slightly raised plaque on the anterior surface of the right leg showing pigmentation, depigmentation and atrophy. Portions of the area are red. There is a fixed nodular feeling to the lesion, and some deep-seated translucent nodules are seen. A sharply marginated dime-sized ulcer with a purulent base occupies the center of the lesion. There