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Desipramine-Induced Blue-Gray Photosensitive Pigmentation
- Source :
- Archives of Dermatology; April 1993, Vol. 129 Issue: 4 p474-476, 3p
- Publication Year :
- 1993
-
Abstract
- † BACKGROUND.— Blue-gray pigmentation of the skin can be elicited by several medications. We report the first case (to our knowledge) of desipramine-induced photosensitive blue-gray pigmentation. OBSERVATIONS.— Diffuse blue-gray pigmentation on sun-exposed surfaces was noted in a healthy 48-year-old woman who had been taking desipramine hydrochloride for 8 years. Ultrastructural studies demonstrated the presence of melanin and homogeneous electron-dense material in the dermis. CONCLUSIONS.— We conclude that tricyclic antidepressant agents represent another class of medications responsible for blue-gray cutaneous pigmentation.(Arch Dermatol. 1993;129:474-476)
Details
- Language :
- English
- ISSN :
- 0003987X and 15383652
- Volume :
- 129
- Issue :
- 4
- Database :
- Supplemental Index
- Journal :
- Archives of Dermatology
- Publication Type :
- Periodical
- Accession number :
- ejs28481577
- Full Text :
- https://doi.org/10.1001/archderm.1993.01680250086012