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Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics

Nup50 is required for cell differentiation and exhibits transcription-dependent dynamics

Authors :
Buchwalter, Abigail L.
Liang, Yun
Hetzer, Martin W.
Source :
Molecular Biology of the Cell; August 2014, Vol. 25 Issue: 16 p2472-2484, 13p
Publication Year :
2014

Abstract

Nup50 is a mobile nucleoporin with a pronounced presence both at the nuclear pore complex and in the nucleoplasm that can move between these different localizations. The dynamic behavior of Nup50 in both locations is dependent on active transcription by RNA polymerase II.

Details

Language :
English
ISSN :
10591524 and 19394586
Volume :
25
Issue :
16
Database :
Supplemental Index
Journal :
Molecular Biology of the Cell
Publication Type :
Periodical
Accession number :
ejs33545399
Full Text :
https://doi.org/10.1091/mbc.e14-04-0865