On facilitation of transmitter release at the toad neuromuscular junction

1. The time dependence of the increase in amplitude (facilitation) of a second end‐plate potential (e.p.p.) elicited within 10–100 msec of a preceding e.p.p. was examined at neuromuscular junctions in sartorius muscles of toads. Facilitation was defined by two characteristics, initial facilitation and the time constant of its exponential decay.