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Novel pyrazole fused heterocyclic ligands: Synthesis, characterization, DNA binding/cleavage activity and anti-BVDV activity
- Source :
- Chinese Chemical Letters; May 2015, Vol. 26 Issue: 5 p534-538, 5p
- Publication Year :
- 2015
-
Abstract
- We have synthesized some novel pyrazoles fused heterocyclic derivatives. With 3b-Cu2+and 3c-Cu2+, the plasmid DNA could be cleaved completely. Meanwhile, Compound 3lshowed the highest antiviral activity (EC50=0.12μmol/L).
Details
- Language :
- English
- ISSN :
- 10018417
- Volume :
- 26
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Chinese Chemical Letters
- Publication Type :
- Periodical
- Accession number :
- ejs34693227
- Full Text :
- https://doi.org/10.1016/j.cclet.2015.01.006