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Increase of Urinary Citrovorum Factor Activity in Patients Receiving Methotrexate (Amethopterin)

Authors :
Li, M. C.
Nixon, W. E.
Freeman, M. V.
Source :
Experimental Biology and Medicine; January 1958, Vol. 97 Issue: 1 p29-32, 4p
Publication Year :
1958

Abstract

L. citrovorum#8081/A of Hutchinson's laboratory has been shown to be an appropriate microorganism for measurement of urinary CF activity under the experimental conditions described. A 3–5 fold increase of urinary CF activity was repeatedly observed in subjects receiving large doses of methotrexate (Amethopterin). The possible sources of this increased urinary CF activity were discussed.

Details

Language :
English
ISSN :
15353702 and 15353699
Volume :
97
Issue :
1
Database :
Supplemental Index
Journal :
Experimental Biology and Medicine
Publication Type :
Periodical
Accession number :
ejs35576048
Full Text :
https://doi.org/10.3181/00379727-97-23638