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Are effects of common ragwort in the Ames test caused by pyrrolizidine alkaloids?

Authors :
Bovee, Toine F.H.
Helsdingen, Richard J.R.
Hoogenboom, Ron L.A.P.
de Nijs, Monique W.C.M.
Liu, Xiaojie
Vrieling, Klaas
Klinkhamer, Peter G.L.
Peijnenburg, Ad A.C.M.
Mulder, Patrick P.J.
Source :
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis; August 2015, Vol. 778 Issue: 1 p1-10, 10p
Publication Year :
2015

Abstract

•Extracts of Senecio jacobaeatest positive in the Ames test.•Extracts of Senecio jacobaeacontain substantial amounts of PAs.•Positive Ames test outcomes were not caused by PAs, but by free quercetin.

Details

Language :
English
ISSN :
13861964
Volume :
778
Issue :
1
Database :
Supplemental Index
Journal :
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis
Publication Type :
Periodical
Accession number :
ejs35956476
Full Text :
https://doi.org/10.1016/j.mrfmmm.2015.05.006