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Experiences with Danazol (an antigonadotropin) in the treatment of infertility
- Source :
- American Journal of Obstetrics and Gynecology; March 1974, Vol. 118 Issue: 6 p783-787, 5p
- Publication Year :
- 1974
-
Abstract
- An antigonadotropic agent, Danazol, was used in the management of 48 patients with either primary or secondary sterility. All patients were infertile for 3 or more years before Danazol was employed. In Group 1, 11 of 21 had proved endometriosis histologically; the rest had suspected endometriosis by history and examination. In the second group of 27, no reason for infertility was found. A dose of 200 mg. was given orally for 100 days to all patients, but, in the group with endometriosis, the dosage was increased to 400 mg. in 3 and 800 mg. in 5 in order to induce abatement of severe pelvic discompfort. None conceived while on therapy while about 40 per cent did conceive within 4 months after discontinuation of the drug.
Details
- Language :
- English
- ISSN :
- 00029378 and 10976868
- Volume :
- 118
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- American Journal of Obstetrics and Gynecology
- Publication Type :
- Periodical
- Accession number :
- ejs36797465
- Full Text :
- https://doi.org/10.1016/0002-9378(74)90488-8