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Effect of Quinine on the Morphology of Mouse Testes

Authors :
Borovskaya, T.
Gol'dberg, E.
Abramova, E.
Fomina, T.
Tkachenko, S.
Source :
Bulletin of Experimental Biology and Medicine; October 2000, Vol. 130 Issue: 10 p994-996, 3p
Publication Year :
2000

Abstract

Single injection of quinine in a maximum tolerable dose to BALB/c mice caused morphological changes in the testes and suppressed spermatogenesis. Gonocytes in all layers of the spermatogenic epithelium, interstitial endocrinocytes, and sustenocytes proved to be sensitive to the toxic effect of the drug. The majority of detected morphological changes were reversible.

Details

Language :
English
ISSN :
00074888 and 15738221
Volume :
130
Issue :
10
Database :
Supplemental Index
Journal :
Bulletin of Experimental Biology and Medicine
Publication Type :
Periodical
Accession number :
ejs37748396
Full Text :
https://doi.org/10.1023/A:1002878226901