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Prognostic and Predictive Effect of TP53Mutations in Patients with Non–Small Cell Lung Cancer from Adjuvant Cisplatin–Based Therapy Randomized Trials: A LACE-Bio Pooled Analysis
- Source :
- Journal of Thoracic Oncology; June 2016, Vol. 11 Issue: 6 p850-861, 12p
- Publication Year :
- 2016
-
Abstract
- Tumor protein p53 gene (TP53) mutations are common in stage I through III non–small cell lung cancer, but clinical trials have shown inconsistent results regarding their relationship to the effects of adjuvant therapy. The objective is to clarify their putative prognostic and predictive effects.
Details
- Language :
- English
- ISSN :
- 15560864 and 15561380
- Volume :
- 11
- Issue :
- 6
- Database :
- Supplemental Index
- Journal :
- Journal of Thoracic Oncology
- Publication Type :
- Periodical
- Accession number :
- ejs38161110
- Full Text :
- https://doi.org/10.1016/j.jtho.2016.02.002