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A large Rab GTPase encoded by CRACR2Ais a component of subsynaptic vesicles that transmit T cell activation signals

Authors :
Srikanth, Sonal
Kim, Kyun-Do
Gao, Yuanyuan
Woo, Jin Seok
Ghosh, Shubhamoy
Calmettes, Guillaume
Paz, Aviv
Abramson, Jeff
Jiang, Meisheng
Gwack, Yousang
Source :
Science Signaling; March 2016, Vol. 9 Issue: 420 pra31-ra31, 1p
Publication Year :
2016

Abstract

Recruitment of intracellular vesicles containing the large GTPase CRACR2A to the immunological synapse mediates T cell receptor signaling.

Details

Language :
English
ISSN :
19450877 and 19379145
Volume :
9
Issue :
420
Database :
Supplemental Index
Journal :
Science Signaling
Publication Type :
Periodical
Accession number :
ejs38416813
Full Text :
https://doi.org/10.1126/scisignal.aac9171