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Results from Oritavancin Resistance Surveillance Programs (2011 to 2014): Clarification for Using Vancomycin as a Surrogate To Infer Oritavancin Susceptibility
- Source :
- Antimicrobial Agents and Chemotherapy; February 2016, Vol. 60 Issue: 5 p3174-3177, 4p
- Publication Year :
- 2016
-
Abstract
- ABSTRACTMeasurement of vancomycin susceptibility has been shown to be highly predictive as a surrogate measure of oritavancin susceptibility among clinically indicated Gram-positive species. Results of studying over 30,000 pathogens (from 2011 to 2014) by cross-susceptibility analysis and determining the poor reproducibility of oritavancin-nonsusceptible results showed nearly perfect surrogate testing accuracy (99.86 to 99.94%). Any isolate of an indicated organism species with locally reproducible oritavancin-nonsusceptible results (extremely rare) should be referred to a reference laboratory for confirmation of the results and determination of the resistance mechanism.
Details
- Language :
- English
- ISSN :
- 00664804 and 10986596
- Volume :
- 60
- Issue :
- 5
- Database :
- Supplemental Index
- Journal :
- Antimicrobial Agents and Chemotherapy
- Publication Type :
- Periodical
- Accession number :
- ejs38643830
- Full Text :
- https://doi.org/10.1128/AAC.03029-15