ChemInform Abstract: Regiospecific Functionalization of Dimetallated Isopropenylacetylene, a Synthetic Equivalent of the Isoprene “Anion”. An Efficient Synthesis of the Bark Beetle Pheromones (.+‐.)‐Ipsenol and (.+‐.)‐Ipsdienol.

Isopropenylacetylene (I) is metallated to give the bislithio compound (III) which reacts with various electrophiles such as (IV) to form the enyne derivatives (V).