ChemInform Abstract: Synthesis and Structure‐Activity Relationships of a Novel Class of 5‐Lipoxygenase Inhibitors. 2‐(Phenylmethyl)‐4‐hydroxy‐3,5‐dialkylbenzofurans: The Development of L‐656,224.

Authors :: LAU, C. K.
BELANGER, P. C.
SCHEIGETZ, J.
DUFRESNE, C.
WILLIAMS, H. W. R.
MAYCOCK, A. L.
GUINDON, Y.
BACH, T.
DALLOB, A. L.
DENIS, D.
FORD‐HUTCHINSON, A. W.
GALE, P. H.
HOPPLE, S. L.
LETTS, L. G.
LUELL, S.
MCFARLANE, C. S.
MACINTYRE, E.
MEURER, R.
MILLER, D. K.
PIECHUTA, H.
RIENDEAU, D.
ROKACH, J.
ROUZER, C.
Source :: ChemInform; December 1989, Vol. 20 Issue: 49 pno-no
Publication Year :: 1989
Abstract: Coupling of the substituted 2‐acetylresorcinols (I) with the phenacyl bromide (II) followed by in situ cyclization gives the 2‐benzoylbenzofurans (III).

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