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Ionic immune suppression within the tumour microenvironment limits T cell effector function
- Source :
- Nature; September 2016, Vol. 537 Issue: 7621 p539-543, 5p
- Publication Year :
- 2016
-
Abstract
- Potassium ions released by necrotic cells in tumours impair T cell function by increasing the intracellular potassium concentration in vitroand in vivo.
Details
- Language :
- English
- ISSN :
- 00280836 and 14764687
- Volume :
- 537
- Issue :
- 7621
- Database :
- Supplemental Index
- Journal :
- Nature
- Publication Type :
- Periodical
- Accession number :
- ejs40058069
- Full Text :
- https://doi.org/10.1038/nature19364