Significance of serum 8-Hydroxydeoxyguanosine levels to the intima-media thickness of the carotid artery in type 2 diabetes

Background: Cardiovascular disease is the largest cause of morbidity and mortality in patients with type 2 diabetes mellitus. Interestingly, previous studies demonstrated that type 2 diabetic patients had a significantly higher concentration of 8-Hydroxydeoxyguanosine (8-OHdG) although it role in the pathogenesis of carotid artery atheroma and insulin resistance has not been identified.