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The BDNFVal66Met polymorphism moderates the effect of cognitive reserve on 36-month cognitive change in healthy older adults

Authors :
Ward, David D.
Andel, Ross
Saunders, Nichole L.
Thow, Megan E.
Klekociuk, Shannon Z.
Bindoff, Aidan D.
Vickers, James C.
Source :
Alzheimer's & Dementia: Translational Research & Clinical Interventions; September 2017, Vol. 3 Issue: 3 p323-331, 9p
Publication Year :
2017

Abstract

Cognitive reserve (CR) and BDNFVal66Met are independently associated with the rate of cognitive decline in preclinical Alzheimer's disease. This study was designed to investigate the interactive effects of these variables on 36-month cognitive change in cognitively intact older adults.

Details

Language :
English
ISSN :
23528737
Volume :
3
Issue :
3
Database :
Supplemental Index
Journal :
Alzheimer's & Dementia: Translational Research & Clinical Interventions
Publication Type :
Periodical
Accession number :
ejs41895185
Full Text :
https://doi.org/10.1016/j.trci.2017.04.006