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Deoxycholic Acid, a Metabolite of Circulating Bile Acids, and Coronary Artery Vascular Calcification in CKD
- Source :
- American Journal of Kidney Diseases; January 2018, Vol. 71 Issue: 1 p27-34, 8p
- Publication Year :
- 2018
-
Abstract
- Vascular calcification is common among patients with chronic kidney disease (CKD), and it is associated with all-cause and cardiovascular disease mortality. Deoxycholic acid, a metabolite of circulating bile acids, is elevated in CKD and induces vascular mineralization and osteogenic differentiation in animal models.
Details
- Language :
- English
- ISSN :
- 02726386 and 15236838
- Volume :
- 71
- Issue :
- 1
- Database :
- Supplemental Index
- Journal :
- American Journal of Kidney Diseases
- Publication Type :
- Periodical
- Accession number :
- ejs42837503
- Full Text :
- https://doi.org/10.1053/j.ajkd.2017.06.017