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Chirality Sensing of α-Hydroxyphosphonates by N-tert-Butyl Sulfinyl Squaramide

Authors :
Li, Yao
Yang, Guo-Hui
He, Cyndi Qixin
Li, Xin
Houk, K. N.
Cheng, Jin-Pei
Source :
Organic Letters; 20240101, Issue: Preprints
Publication Year :
2024

Abstract

N-tert-Butyl sulfinyl squaramides were used for chiral discrimination of α-hydroxyphosphonates using 31P NMR. A free energy relationship study indicates that both steric and the electronic effects influence the chiral recognition of the donors.

Details

Language :
English
ISSN :
15237060 and 15237052
Issue :
Preprints
Database :
Supplemental Index
Journal :
Organic Letters
Publication Type :
Periodical
Accession number :
ejs42905056
Full Text :
https://doi.org/10.1021/acs.orglett.7b01743