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TRIF-dependent Toll-like receptor signaling suppresses Scd1transcription in hepatocytes and prevents diet-induced hepatic steatosis

Authors :
Chen, Jing
Li, Jin
Yiu, Jensen H. C.
Lam, Jenny K. W.
Wong, Chi-Ming
Dorweiler, Bernhard
Xu, Aimin
Woo, Connie W.
Source :
Science Signaling; August 2017, Vol. 10 Issue: 491
Publication Year :
2017

Abstract

A TRIF-dependent pathway that restricts viral infection also prevents diet-induced hepatic steatosis.

Details

Language :
English
ISSN :
19450877 and 19379145
Volume :
10
Issue :
491
Database :
Supplemental Index
Journal :
Science Signaling
Publication Type :
Periodical
Accession number :
ejs42970823
Full Text :
https://doi.org/10.1126/scisignal.aal3336