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Effects of acarbose on cardiovascular and diabetes outcomes in patients with coronary heart disease and impaired glucose tolerance (ACE): a randomised, double-blind, placebo-controlled trial

Authors :
Holman, Rury R
Coleman, Ruth L
Chan, Juliana C N
Chiasson, Jean-Louis
Feng, Huimei
Ge, Junbo
Gerstein, Hertzel C
Gray, Richard
Huo, Yong
Lang, Zhihui
McMurray, John J
Rydén, Lars
Schröder, Stefan
Sun, Yihong
Theodorakis, Michael J
Tendera, Michal
Tucker, Lynne
Tuomilehto, Jaakko
Wei, Yidong
Yang, Wenying
Wang, Duolao
Hu, Dayi
Pan, Changyu
Keenan, Joanne
Milton, Joanne
Doran, Zoe
Bray, Chris
Rouleau, Jean L
Collier, Jane
Pocock, Stuart
Standl, Eberhard
Swedberg, Karl
Weng, Jianping
Zhao, Dong
Petrie, Mark C
Connolly, Eugene
Jhund, Pardeep
MacDonald, Michael
Myles, Rachel C
Bai, Rong
Li, Jing
Liu, Zhaoping
Liu, Zhenyu
Peng, Dantao
Tong, Qiguang
Wang, Chunxue
Yan, Xiaowei
Zhang, Yuqing
Zhou, Jingmin
Sattar, Naveed
Fisher, Miles
Petrie, John R
Bethel, M Angelyn
Xu, Wen
Hearn, Sarah
Kappai, Anurag
Su, Shu-Yi
Liyanage, Winitha
Paul, Sanjoy
Pozzi, Emanuela
Ring, Arne
Athwal, Rajbir
Batra, Priyanka
Ferch, Andrea
Groves, Natasha
Kennedy, Irene
Nawalaniec, Olga
Patel, Yash
Roberts, Rachel
Rush, Victoria
Starrett, Jayne
Tang, Jennifer
Bi, Jing
Jiang, Zhe
Wei, Hua
Wei, Xiaoshuai
Zhang, Xuan
Yin, Jun
Sun, Yu
Hu, Rong
Liu, Yang
Long, Jianjing
Long, Yuefeng
Qiao, Guofang
Qiao, Haoyi
Sun, Xiaochun
Zhang, Yucheng
Zhou, Jing
Wang, Bangning
Chen, Bin
Deng, Lili
Han, Xiaoning
Hu, Taohong
Hua, Qi
Huo, Yanming
Li, Hongmei
Li, Hongwei
Liu, Lihua
Lu, Juming
Ma, Changsheng
Peng, Jianjun
Pi, Lin
Wang, Bin
Wei, Guanglin
Yang, Ming
Zhang, Shuyang
Zhang, Likun
Zhao, Xia
Zhou, Yujie
Shi, Libin
Wang, Mingsheng
Wu, Lirong
Han, Lei
Liao, Ronghong
Ran, Boli
She, Qiang
Tan, Jiancong
Xia, Mei
Yang, Chengming
Chen, Lianglong
Xiong, Shangquan
Yu, Ling
Pu, Xiaodong
Wang, Yan
Xie, Qiang
Chen, Cibin
Chen, Jiyan
Dong, Yugang
Wu, Zhaohui
Yuan, Yong
Zhou, Wanxing
Zhou, Shuxian
Chen, Xiaochao
Wu, Chun
Zhang, Aidong
Li, Zicheng
Lai, Shayi
Yang, Jin
Wei, Jinru
Kuang, Riyu
Zhao, Zilin
Zhong, Guoqiang
Cao, Xufen
Hao, Yuming
Liu, Gang
Wang, Dongmei
Fang, Hui
Kong, Lingjun
Li, Haitao
Wang, Changqing
Wang, Li'na
Li, Xueqi
Dong, Pingshuan
Zhang, Shouyan
Liu, Xincan
Zhao, Yulan
Liu, Hengliang
Gu, Ye
Liao, Yuhua
Su, Xi
Wang, Daowen
Wang, Hairong
Yang, Bo
Guo, Ying
Ouyang, Ding'an
Yang, Tianlun
Zhang, Yumin
Han, Yajun
Lin, Xuefeng
Zhao, Ruiping
Man, Ronghai
Bian, Rongwen
Biao, Xu
Hasimu, Buaijiaer
Jin, Hui
Liu, Ping
Yu, Jiangyi
Zhang, Hang
Xu, Chongli
Guo, Yan
Lv, Ke
Tao, Yijia
Xu, Xin
Yang, Zhenyu
Li, Dongye
Qi, Chunmei
Zhang, Guohui
Gu, Xiang
Hong, Lang
Hu, Ling
Li, Juxiang
Yang, Ping
Liu, Bin
Wang, Gang
Lin, Hailong
Liu, Jun
Zhang, Shuying
Han, Ping
Jin, Yuanzhe
Li, Ling
Li, Zhanquan
Luan, Hong
Song, Mei
Xue, Li
Hua, Yu
Liu, Dongwu
Yuan, Zuyi
Ye, Jixian
Gao, Feng
Feng, Jinhua
Wang, A'li
Ye, Shengming
Li, Xiaoyan
Su, Guohai
Zhang, Shufang
Hou, Zishan
Jiang, Wenbin
Zhou, Changyong
Wang, Yanping
Qi, Wenbo
Bao, Xiaomei
Feng, Bo
Gong, Hui
Gu, Shuiming
Gu, Mingjun
Guo, Xingui
He, Ben
Huang, Ying
Jiang, Jinfa
Jiang, Yifeng
Jin, Huigen
Li, Yuehua
Liu, Qiliang
Lu, Guoping
Miao, Peizhi
Qin, Yongwen
Wang, Bin
Wang, Yuanming
Wu, Shiyao
Xu, Yawei
Ma, Jin
Chen, Xiaoping
Liu, Xiumin
Tang, Jianing
Wang, Jingping
Chen, Xiaoping
Tao, Jianhong
Zhang, Jun
Zhang, Tingjie
Li, Decai
Du, Xinping
Jiang, Tiemin
Lin, Jingna
Lu, Chengzhi
Ma, Hongjun
Gao, Bo
Guo, Xukun
Li, Tong
Zheng, Shaoxiong
Li, Zhongcheng
Zhao, Shuwu
Qiu, Qiang
Li, Kaili
Liu, Junming
Tang, Baopeng
Yuan, Zhanjun
Zhou, Jianhua
Bai, Wenwei
Guo, Tao
Zhang, Ge
Zhang, Hong
Hao, Yinglu
Fu, Guosheng
Tang, Lijiang
Chen, Jialun
Source :
The Lancet Diabetes & Endocrinology; November 2017, Vol. 5 Issue: 11 p877-886, 10p
Publication Year :
2017

Abstract

The effect of the α-glucosidase inhibitor acarbose on cardiovascular outcomes in patients with coronary heart disease and impaired glucose tolerance is unknown. We aimed to assess whether acarbose could reduce the frequency of cardiovascular events in Chinese patients with established coronary heart disease and impaired glucose tolerance, and whether the incidence of type 2 diabetes could be reduced.

Details

Language :
English
ISSN :
22138587 and 22138595
Volume :
5
Issue :
11
Database :
Supplemental Index
Journal :
The Lancet Diabetes & Endocrinology
Publication Type :
Periodical
Accession number :
ejs43620570
Full Text :
https://doi.org/10.1016/S2213-8587(17)30309-1